Taste receptors and testes. What is the relation?

We generally have an opinian that testes is the organ in the body dealing with reproduction and related function. Testes is known to have cells and receptors which involve in various functions. But we are not aware of a astonishing fact. Have anyone ever wondered that some irrelated receptors like taste receptors are presnt in the testes and play a prime role in reproduction and fertility? Yes it does

TAS1R taste receptors are the receptors responsible and involved in sugar sensing. According to the previous studies their function was unknown though they were found in testes and sperm. But in a study by Bedrch Mosinger et al., this function was confirmed. Sperm formation in animals without functional TAS1R3 and GNAT3 is compromised, with malformed and immotile sperm. The hypothesis in this study revealed that even low levels of these compounds can lower sperm count and negatively affect human male fertility, which common mouse toxicology assays would not reveal. The study also speculated that TAS1R3 and GNAT3 activators may help infertile men, particularly those that are affected by some of the mentioned inhibitors and/or are diagnosed with idiopathic infertility involving signaling pathway of these receptors.

We need more confirmations and proofs to support this research as this may lead us to many different ways and pave path towards 100% fertility in males.

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